Using e-cigarettes is no safer than smoking tobacco with nicotine, scientists warned after finding the vapour damages DNA and could cause cancer.
Researchers at the University of California created an extract from the "smoke" of e-cigarettes and used it to treat human cells in a laboratory.
The exposed cells developed DNA damage and died far sooner than untreated ones.
Nicotine-free e-cigarettes caused 50 per cent more DNA strand breaks; for those with nicotine, the damage rose three-fold in eight weeks.
Dr Jessica Wang-Rodriguez, professor of pathology at the university in San Diego, said: "Our study strongly suggests that electronic cigarettes are not as safe as their marketing makes them appear. E-cigarettes on the whole have something to do with increased cell death. Based on the evidence to date I believe they are no better than smoking."