The effects are gruesome. Hangovers vary in intensity from merely feeling you're 30 seconds behind the rest of the world to the full-on, goblins-stabbing-your-eyeballs, dragon's-breath, shaking, guilt-racked nervous hell that is a classic hangover.
With little medically known about hangovers, perhaps it isn't surprising that a cure hasn't been found, but there are some tips you can rely on to minimise the impact.
Fried food is a wholly false cure for a hangover, which I can tell you from in-depth research. It may make you feel better briefly, but that's a fool's cure, as the usual result is that your symptoms have merely been increased by nausea and possibly the runs.
There have been some attempts at cures. I once tried a substance that went under the name of RU-21. Apparently developed by the KGB to allow their spies to outdrink their degenerate capitalist running dog counterparts, it relied on isolating one of the most toxic elements of alcohol, acetaldehyde, and preventing it from being processed by the liver.
I experimented with this and it worked - up to a point. The major flaw was that you needed to take two tablets before starting your night out and then - and this is where the crucial flaw arose - you had to remember to take two more before you went to bed.
When I remembered the dosage correctly, it worked beautifully, but if you forget those pre-bed tablets, you're in for a grimly predictable morning.
Perhaps the best cure of all is to monitor your drinking and don't go out with the sole intention of getting utterly bladdered.
A glass of water between each drink works well, helping to replace the hydration stolen by alcohol and, boring though I may sound here, moderation should be your watchword.
Let's be honest, we've all been there - let's not go back there again.