According to the 2018 Global Burden of Disease study, headaches are among the most prevalent and disabling conditions worldwide. Photo / Getty Images
From the pounding of a migraine to a low-level nagging discomfort, few of us escape the pain of a headache.
According to a 2022 study published in The Journal of Headache and Pain, more than half the world’s population – 52 per cent – have experienced some type of “primary”headache during the past year.
There are two types of headache, says Peter Goadsby, professor of neurology and director of the National Institute for Health Research, Wellcome Trust King’s Clinical Research Facility, King’s College London.
“Primary headache disorders are those where the headache is the problem and there’s nothing else going on,” he says, “while secondary headache disorders are when the headache is caused by something like a brain tumour or meningitis, or if you’ve banged your head.
“Migraines are the most common cause of primary headache disorders and women are three times more likely to get them than men, thanks to hormonal fluctuations.”
According to the 2018 Global Burden of Disease study, headaches are among the most prevalent and disabling conditions worldwide. But what are the likely causes and what can we do about them?
The nothing-to-worry-about tension headache
These are what we think of as normal, everyday headaches. Tension-type headaches (TTH) typically feel like a tight band or pressure around your head, with pain on both sides, but unlike migraines, you can have one and still carry on with your usual activities.
Studies show a link between poor sleep quality and TTH. In one study, 26-72 per cent of patients with TTH identified “lack of sleep” as a factor triggering their headaches.
“Like migraine, a tension-type headache can be caused by missed meals, lack of sleep, dehydration, anxiety and stress,” says Prof Anne MacGregor, specialist in headache and sexual and reproductive healthcare at Barts Health NHS Trust.
“But unlike a migraine, it can quickly be resolved with food, hydration, sleep or taking time out to decompress.”
What to do about it
Address the above lifestyle factors – there could be an easy solution. Muscle tension is another common trigger for tension-type headaches, whether from sitting hunched over a computer, lifting a heavy object or even wearing a badly-fitting bra, as the weight of the breasts may cause stress on the shoulders, back and neck – so check you’re doing these correctly.
Simple painkillers that you can buy over the counter, such as ibuprofen, paracetamol and aspirin, will usually work to resolve a TTH within 20 minutes.
“Beware of taking painkillers too often, as if regularly taken on three or more days a week, they can result in medication-overuse headache,” says Prof MacGregor. “In simple terms, overuse shuts down the body’s natural ability to control pain.”
Signs it’s a migraine attack
About 10 million people in the United Kingdom live with migraine, according to the latest report from The Migraine Trust, and migraines are more common than epilepsy, diabetes and asthma combined.
“Migraines occur in attacks, sometimes several times a month or they may occur just once or twice a year, and they can last anything from a few hours to a few days,” says Prof MacGregor.
“The key features are episodes of headache on one side or both sides of your head, accompanied by nausea (two-thirds of sufferers have this) and sensitivity to light and sound. The pain is so bad that sufferers often find it difficult to continue their usual daily activities and may have to stay in bed.”
A predisposition to migraines can be passed down through families. Triggers include skipped meals, dehydration, sleep deprivation and a lack of exercise.
What to do about it
“A healthy brain needs regular food, water, sleep and exercise, so aim for consistency in these areas,” adds Prof MacGregor.
Doctors recommend taking aspirin: Studies have shown that a single dose of 900mg aspirin is as effective as 50mg-100mg of sumatriptan, a prescription medication for migraines. But, for many, a cold compress and a dark, quiet room work just as well.
Those who suffer most might be prescribed a medication called triptan – not a painkiller per se, but specific to migraine management. “In the early part of a migraine attack, blood vessels on the surface of the brain dilate and trigger a cascade of chemical changes,” says Prof MacGregor.
“These are processed by the brain and ultimately perceived as pain and all the other typical migraine symptoms of nausea, light sensitivity and so on. Triptans constrict these blood vessels and prevent the headache developing into a full-blown migraine attack.”
A new type of treatment known as CGRP mAbs is the first preventative medicine to be prescribed for migraine, given by injection. It’s now available on the UK NHS, but can only be offered when all other treatments have failed.
Cluster headaches: When the pain is so bad, you can’t sit still
Sometimes referred to as “suicide headaches” because of the severity of the pain, cluster headaches are thankfully uncommon, affecting about two in 1,000 people. They are more common in men than women.
Attacks are characterised by severe pain on one side of the head, accompanied by agitation and restlessness.
“Such headaches typically occur at night, in clusters lasting six to eight weeks, often at the same time of year, with periods of remission in between,” says Prof MacGregor.
“Attacks tend to come on quickly, last between 30 to 90 minutes, and can occur several times a day, too.
Attacks often wake the sufferer within an hour of falling asleep and can be triggered by alcohol and hot, spicy foods.
“The cause of cluster headaches is unknown, but research has highlighted changes in a part of the brain known as the hypothalamus, the area that controls the body clock, which might explain why clusters often occur at the same time of year and the same time of day or night,” adds Prof MacGregor.
What to do about it
Effective treatments include sumatriptan injections and nasal sprays, which work to constrict blood vessels. These stop pain signals being sent to the brain and block the release of certain natural substances that cause pain, nausea and other symptoms of migraine.
New research is also underway looking at the cluster-relieving effects of psilocybin, a psychoactive compound found in magic mushrooms.
Is it my hormones?
According to the National Migraine Centre, more than half of women who get migraines notice a link with their periods. “Some women are sensitive to the natural drop in oestrogen just before or in the first few days of their period, or during the hormone-free interval of combined hormonal contraception,” says Prof MacGregor.
The best way to tell if your headaches are hormonal is to keep a diary over several months. If they’re linked, see your GP, as managing the period problem may itself help the headaches.
What to do about it
“Treatment to prevent attacks can range from standard migraine prevention to hormonal contraceptives,” says Prof MacGregor. “And if you continue to have headaches during the hormone-free week of contraception, you may be able to take several packs for three to five months without a break.”
Hormone headaches may also increase in prevalence during perimenopause, due to the natural hormone fluctuations that occur at this stage of life. A prescription of HRT from your GP or specialist, who may advise a patch or gel with continuous progesterone, may help.
Hormonal headaches may get more severe in the run-up to the menopause, due to the drop in oestrogen, but the good news is that the menopause tends to get rid of them altogether.