Migraines have just one cause that is to blame for every one of their debilitating symptoms, ranging from extreme headaches to nausea, says a groundbreaking study.
If the research is confirmed it could pave the way to a cure for the crippling condition said to afflict millions of people around the world.
And the solution could be as simple as taking the right vitamin or supplement.
Jonathan Borkum, a clinical psychologist and professor at the University of Maine, in the US, studied 2,000 papers on migraines - every one published between 1990 and 2014.
He concluded that the root of the problem is a surplus of "free radicals" - corrosive molecules produced as our bodies process oxygen. All of the known triggers for migraine, such as dehydration and air pollution, can lead to over-production of free radicals, which in turn result in a condition called "oxidative stress".