Connie Culp, an Ohio woman who became the first recipient of a partial face transplant after surviving a botched murder-suicide attempt, died Thursday at age 57.
Culp's cause of death has yet to be revealed, but her passing was confirmed by the Cleveland Clinic's Dermatology and Plastic Surgery Institute, where she underwent her surgical procedure.
"Connie was an incredibly brave, vibrant woman, and an inspiration to many," Dr Frank Papay, chairman of the clinic's Dermatology and Plastic Surgery Institute, said in a statement.
"Her strength was evident in the fact that she had been the longest-living face transplant patient to date. She was a great pioneer and her decision to undergo a sometimes-daunting procedure is an enduring gift for all of humanity."