The advice "beer before wine and feel you'll fine, wine before beer and you'll feel queer" has long been followed by drinkers eager to avoid a hangover.
However, a study by the University of Cambridge and German scientists suggests that the order of drinking does little to stave off nausea and a throbbing head.
Researchers asked volunteers to drink two and a half pints of beer followed by four large glasses of wine, while a second group had the same amount of alcohol in reverse order.
The next day they were asked to rate their hangover, taking into account thirst, fatigue, headache, dizziness, nausea, stomach ache, increased heart rate and loss of appetite.
A week later the groups were asked to switch the order of drinks to see whether it made any difference.