"It's more than just the police," Mr Rodríguez captioned the two photos and it was quickly retweeted more than 180,000 times.
The tweet attracted hundreds of responses, with many saying it was one of the best examples of the unconscious bias that exists towards black people.
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But others claimed it wasn't an issue of race, saying that big US chains like Walmart would often have extra security for items if they were frequently stolen from a store.
Soon others were sharing other instances of products for sale in stores that appeared to show bias towards people of colour.
One person posted a TikTok video of how sunscreen for darker skin was displayed behind a pillar despite plenty of room on other shelves.
The Twitter debate comes as George Floyd's funeral took place this week and protests continue across the country.
More than 500 mourners wearing face masks to protect against the coronavirus packed a Houston church a little more than two weeks after Mr Floyd was pinned to the pavement by a white Minneapolis police officer who put a knee on his neck for what prosecutors said was 8 minutes and 46 seconds.
In the past two weeks, amid the furore over Mr Floyd's death, sweeping and previously unthinkable things have taken place: Confederate statues have been toppled, and many cities are debating overhauling, dismantling or cutting funding for police departments.
Authorities in some places have barred police from using chokeholds or are otherwise rethinking policies on the use of force.
Some of the mostly peaceful demonstrations that erupted after Mr Floyd's death were marked by bursts of arson, assaults, vandalism and smash-and-grab raids on businesses, with more than 10,000 people arrested.
But protests in recent days have been overwhelmingly peaceful.
– With AP