RTL said the new arrivals make her the world's oldest mother of quadruplets. The boys have been named Dries, Bence and Fjonn and the girl Neeta.
Raunigk made headlines 10 years ago when she gave birth to her 13th child, Lelia, at the age of 55.
"At first, I only wanted one child," she said then. "Not all were planned. But then things happen. I'm not a planner but rather spontaneous. And children keep me young."
Raunigk again made headlines in April when the German press reported that her latest artificial insemination attempt had resulted in a quadruple pregnancy.
At the time, she said she decided to try to have another child because her youngest daughter, who is 9, wanted a little brother or sister, according to RTL.
The tabloid Bild am Sonntag quoted Raunigk, whose oldest daughter is reportedly 44, recalling that it was "a shock" when the doctors first broke the news to her of a quadruple pregnancy.
"After the doctor discovered there were four, I had to give it some thought to begin with."
But she did not consider reducing the number of embryos and said she had no reservations about the challenge facing her.
"I'm not actually afraid. I simply assume I'll remain healthy and fit. In matters of organisation I have enough experience, that's not new for me," she told Bild.
Asked about moral doubts, RTL quoted her as asking: "How does one have to be at 65? One must apparently always fit some cliches which I find rather tiring.
"I think one must decide that for oneself."
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- Observer, AFP