Whio, kereru, kiwi and New Zealand native bats will benefit from an aerial 1080 operation needed to eradicate bovine TB in the Ruapehu District.
The operation, over about 35,000ha, will take place at a time around late July when fine weather is predicted, OSPRI operations extension officer Phillip Dawson said.
The area takes in parts of Tongariro National Park and the Rangataua and Karioi forests, and comes close to Ōhakune and Rangataua.
The aim is to kill possums responsible for spreading TB to cattle and deer. The cattle herds in the area are subject to yearly testing to assess the prevalence of bovine TB.
Consultation with landowners is still happening, to agree the exact boundaries of the operation. Tourist operators, Iwi, hunters, trampers and conservation groups have already been consulted.