Directed by Todd Phillips, Joker also stars Robert De Niro as a TV talk show host named Murray Franklin, and Zazie Beetz (Atlanta) as Sophie Dumond, a single mother who appears to date Fleck.
Phoenix is the latest in a long list of actors to take on the role of the Joker, including the late Heath Ledger in Nolan's The Dark Knight, and Jared Leto in Suicide Squad.
Phoenix's Joker appears more in tune with Ledger's disturbing depiction, although his costuming looks inspired by Cesar Romero's classic 1960's Batman version.
Eagle eyed fans will also notice a brief encounter between the Joker and a young boy, with Phoenix's character reaching through an iron fence and using his fingers to stretch the child's face into a wide clown-like smile.
That kid is played by Dante Pereira-Olsen, who is starring as none other than Bruce Wayne, the boy who will grow to become the Caped Crusader, the Joker's arch nemesis.