The 54-year-old was an industry veteran who also worked on the Star Wars, Harry Potter and Jurassic Park films, recently flying to Morocco to help film Indiana Jones 5.
Over 100 crew members had reportedly gathered in the city to film a major stunt scene. Cupac's grip work involved helping build and maintain the rigging equipment that supports cameras.
The film project appears to have been plagued by problems from the start of filming over the summer.
East London residents revealed in June that the filming on location in their neighbourhood was making life "a living hell" for them. The entire street was blocked off for days and caused major headaches.
Last week, filming was put into jeopardy when Morocco banned flights to and from the UK due to a rise in Covid cases. Harrison Ford, 79, was set to fly into the country just before the travel ban was announced, but it's unclear where he currently is.
Production was also halted for three months after Ford suffered a shoulder injury in June, only returning to set in Italy two weeks ago.
The film has suffered other lengthy delays in production largely due to the Covid-19 pandemic.
Originally set to hit theatres on July 9, 2021, it was pushed back to July 29, 2022. Last month, Disney announced that it is now scheduled for release in 2023.
It's not clear if Cupac's death will prompt further delays in filming.