Contestants will take part in a Cash Builder round, facing five multiple-choice questions and playing for up to £5000 (NZ$9660).
But if they get the first question wrong, they're out of the competition.
The contestants then face off against the Chasers, with the option of facing fewer Chasers for less money and vice versa.
ITV calls it "a brand new prime-time spin on the smash-hit quiz show The Chase, challenging contestants to take on two, three, four or all five Chasers at once".
Show host Bradley Walsh previously said the contestants were brave facing one Chaser, "let alone all five".
"With that group of top quizzing brains working as a team, it's going to take some beating. But I can't wait to see who's going to take them on."
Sinha told Newstalk ZB's Mike Hosking earlier this week that chasers were not "computers".
"We're not machines, we don't know everything," he said, admitting he was jealous of the internet generation who have instant access to information.
And despite his medical degree, Sinha says general knowledge in literature and arts is more useful, as host Walsh is less likely to come out with a difficult science or maths question.
So maybe the new format will see the audience stand a chance against the Chasers.
• Beat The Chasers screens in New Zealand on TVNZ from June 28
