The 42-year-old rapper fell ill at his home in Davie, Florida, with someone calling 911 on Thursday to say the person in distress was "unresponsive with heavy breathing".
The caller said the man in distress had a history of seizures and that they tried to wake him but he was "slobbing out the mouth".
According to TMZ, Rick is being treated in the hospital's cardiac unit, and it is suspected the star suffered a heart attack which manifested itself in respiratory issues.
TMZ also reports the Aston Martin Music rapper has been "hooked up to a machine that's taking over the function of his heart and lungs" whilst he continues to undergo treatment at the hospital.
Sources tell TMZ Rick has been placed on ECMO, or extracorporeal membrane oxygenation, which is a technique used to oxygenate his blood outside of his body, before it's pumped back into his body.
However a family member strongly denied Rick was hospitalised and hip-hop artist Fat Trel took to Instagram to say he had talked to him on the phone and he was in the hospital but not on life support - "[he's] good".
Ross has a history of medical issues and according to TMZ suffered two seizures on two separate flights in October 2011. After initially blaming lack of sleep Ross changed his lifestyle and diet, and slimmed down, dropping up to 100lbs.
Ross, who already has two children from past relationships, welcomed his third child with fitness model Briana Camille in September 2017.