"When you say someone is cancelled, it's not a TV show. It's a human being," Swift said.
"You're sending mass amounts of messaging to this person to either shut up, disappear, or it could also be perceived as, kill yourself."
Swift, who appears on the cover of the style bible's influential September issue, said she realised she "needed to restructure my life because it felt completely out of control".
"I knew immediately I needed to make music about it because I knew it was the only way I could survive it," Swift added.
"It was the only way I could preserve my mental health and also tell the story of what it's like to go through something so humiliating."
Of course, the drama between Swift, Kardashian and West stemmed from the controversial line in West's song, Famous: "For all my South Side n****s that know me best / I feel like me and Taylor might still have sex / Why? I made that bitch famous."
This led Kardashian to leak Snapchat videos that reportedly proved Swift knew about the lyric, which — at the time — she claimed she didn't.
Swift also opened up about how she mended her very public rivalry with Katy Perry after Perry sent Swift an actual olive branch (Perry went on to appear in Swift's video clip for You Need To Calm Down).
"She wrote back, 'This makes me so emotional. I'm so up for this. I want us to be that example. But let's spend some time together. Because I want it to be real.'
"So she (Perry) came over and we talked for hours," Swift said, according to vogue.com.
"We decided the metaphor for what happens in the media is they pick two people and it's like they're pouring gasoline all over the floor.
"All that needs to happen is one false move, one false word, one misunderstanding, and a match is lit and dropped. That's what happened with us.
"It was: Who's better? Katy or Taylor? Katy or Taylor? Katy or Taylor? Katy or Taylor?"
The September issue of US Vogue is out on August 13.
