"Hello, Moe?" he says. "Your sister's being raped."
Tim Winter, president of the advocacy group Parents Television Council, said he's a longtime fan of Matt Groening, creator of The Simpsons, and sought out the trailer when it was released.
"I was blown out of my shoes when I saw the scene with the rape joke in it," Winter said. "It really troubled me."
He said he found it particularly offensive in the context of stories about sexual assaults on college campuses and, most recently, talk about abusive treatment of women by some players in the National Football League. He said when rape is accepted as a punch line for a joke in entertainment, "it becomes less outrageous in real life."
Winter said he wrote to Groening, Family Guy creator Seth MacFarlane and Fox in August, asking that the joke be removed when the episode is shown on television. He said he received no reply.
Fox's entertainment division, through a spokeswoman, said it would not comment on the criticism or whether there are any second thoughts about the joke.
Katherine Hull Fliflet, spokeswoman for the Washington-based Rape, Abuse and Incest National Network, said she did not find the line offensive.
"I think the show is making it clear that rape is not funny by how they are positioning the joke," Fliflet said. "It's my hope that would be the viewers' take-away."
MacFarlane brought up the line during a recent interview with Entertainment Weekly, predicting he will get attacked for it in the media. "But in context," he said, "it's pretty funny."
Winter said he didn't think the subject was worth joking about, and said he was particularly concerned about its exposure to younger viewers who may be fans of The Simpsons, but are not familiar with the Family Guy style of comedy.
"We don't mock certain groups because we realise that it is highly insensitive and morally wrong," he said. "Why wouldn't we do the same thing about sexual assault?"
- AP