"It is an extremely damaging portrayal. Disability should NOT be associated with evil, abnormality, disgust, fear or monsters."
The official Paralympic Games also criticised the film.
In response to the backlash, a Warner Bros spokesperson told Deadline it had been "deeply saddened to learn that our depiction of the fictional characters in The Witches could upset people with disabilities" and that it "regretted any offense caused".
"In adapting the original story, we worked with designers and artists to come up with a new interpretation of the cat-like claws that are described in the book," said the spokesperson.
"It was never the intention for viewers to feel that the fantastical, non-human creatures were meant to represent them."