The game uses GPS on cellphones to track players' movements as they explore different areas to catch different Pokemon.
The app has already rocketed to the top of the charts for iPhone and Android app since its release on July 7.
For those who grew up watching the show on television and playing Pokemon on gameboy, Pokemon Go is a piece of nostalgia.
The design of the game encourages players to move around outside.
The map on the phone's screen depicts real roads, parks and bodies of water around you.
As you walk around, your avatar will move with you, and when you find a Pokemon on your map, tapping on it will initiate an encounter.
To capture it, players must flick "Pokeballs" at the creature that appear at the bottom of the screen. Hitting the Pokemon with a Pokeball will likely capture it, then it is yours.
Players gain levels as a trainer - the higher the level you are, the more powerful Pokemon you are able to find to complete your "Pokedex"- your collection of Pokemon.
"I've never seen so many people walk around the domain following their phones before. I can only assume they are hunting for #Pokemon," said Twitter user Angela.
"Yesterday I stopped at the Sky Tower and asked a group: "Are we all here for the same thing?" We were. #PokemonGo," Troy Rawhiti Forbes posted.
On Friday a teenager in Wyoming found a washed up body whilst virtually hunting for Pokemons. She was apparently attempting to snag a Pokemon from a local river and discovered the body.