In 2018, she shared: "I am a very 'live in the today,' maximum 'live in the next two months' kind of person. But [in] 10 years, I definitely want to have kids. That is, it's going to happen in the next 10 years. Well, hopefully, earlier than that.
"I'm very fond of children and I want to be able to do that."
The couple were forced to spend much of 2021 apart because of Covid-19 travel restrictions.
The Hollywood star admitted the situation was "tough" for them to deal with at the time.
Chopra - who filmed the drama series "Citadel" in London while her husband was based in the US - said: "This year has been really tough. It was really, really tough to be away from home for an entire year, especially at a time when you can't travel to see your family. I was just alone."
Despite this, Chopra insisted they were both understanding of their long-term career ambitions.
She explained: "We talk all the time. We know each other's hearts. We prioritise each other in everything that we do.
"We've had individual careers and we're both very clear about never interfering in each other's professional lives because we're always partners and assets. We'll have an opinion on each other's things, we'll be each other's champions. But those decisions are predominantly for both of us to take, because we've built our careers by ourselves for such a long time."