Natalie Portman's stunning take-down of ex-classmate Jared Kushner

Natalie Portman has a lot to say about Ivanka Trump's husband Jared Kushner. Photo / Getty Images

Natalie Portman has let loose on her former Harvard classmate and friend Jared Kushner in a brutal take-down on national television.

Appearing on Stephen Colbert's The Late Show on Thursday night (local time), the Black Swan actress was asked about a member of her 2003 graduating class: President Trump's son-in-law and adviser Jared Kushner.

And what she had to say was not flattering, despite the fact she admitted the two were once "friendly" — Portman even attended Kushner's wedding to Ivanka Trump in 2009, reports news.com.au.

Colbert probed her for details about their falling out.

"I heard he wasn't that great of a student," the host said.

"That is … true," Portman confirmed, before joking "What can I say on TV?"

Then things took a serious turn.

"Unfortunately, it's not very … there's not a lot funny to say about someone you were friends with becoming a super villain," the Annihilation star said.

"So, you know, it's not funny."

She added: "He said in some interview that the friends he's lost because of politics, it's like exfoliating. And I was like, 'OK, I like the spa metaphors.'"

"So, you're a dead skin cell," Colbert quipped.

"Proudly," she exclaimed.