"I was an actor, I was a musician, I was a sketch artist, and those things aren't available to me now. I don't have the same facility. "
Fox says the diagnosis was a "real shock" when he received the prognosis in 1991.
"I had been feeling some symptoms – a twitch in my pinky, a soreness in my shoulder. I saw this neurologist and did some drunk driving test, and I couldn't do any of that, so he pronounced me as having Parkinson's disease."
That doctor gave Fox just 10 years left to work – but while he has stepped away from leading roles, Fox continues to do voice acting and has been a regular guest star on numerous TV shows, including The Good Wife and Curb Your Enthusiasm.
Fox says he tried to continue acting but first had to relearn the "mechanics of walking" after having a tumour removed from his spine.
An offer came up for a cameo in a Spike Lee movie while he was recuperating, and Fox assured his family that he would be able to do the performance.
"I woke up the next morning, walked into the kitchen, and fell and shattered my arm. I had a plate and 19 pins to restore my humerus bone – and as they say, I broke my humerus is no joke."
Fox says he remains optimistic, as his problems are quite low on the misery index compared to many others.
As part of his recovery, Fox launched The Michael J Fox Foundation, researching to find a cure for Parkinson's.
"We're making great progress and we're opening it up to new areas of research people had never had before. That was my goal."