The deep-voiced actor said society was ready to see a black superhero as a lead character.
Colter said he spoke with many people across the world telling him they related to Cage's character. The original character first appeared in comic books in 1972.
"For people of colour, it inspires them to believe they can be a superhero in their own way, too," said the 1.9m Colter, who bulked up 13kg for the role.
"There's a certain portion of the population that needs to see someone that represents them.
"Sometimes that's not just physically. It's a point of view. I get a lot of fans who are white, Asian, Brazilian. They relate to the character because of their approach to the world. They feel like this guy is blue collared and he is striving to do something with his life with all his limitations financially.
"He's not feeling sorry for himself or having a pity party. He's just trying to keep on, keepin' on. That's what people relate to."
Cage is an ex-convict wrongly imprisoned for a crime he didn't commit, developing his superpowers after a botched experimental procedure.
After clearing his name, he becomes a Harlem celebrity for his heroic efforts to protect the community.
The character has appeared in other Marvel Cinematic Universe shows, including Netflix's Jessica Jones and The Defenders.
In season two, Cage struggles to find a good paying job until he decides to cash in on his abilities as a hero-for-hire.
Colter's fellow cast members called him a "perfect fit" for the Cage role.
"No matter how tired Luke Cage is, he has to protect Harlem. Mike leads our show in the same way," said Simone Missick, who reprises the role of Misty Knight.
"He fits the bill physically.
"He approaches his character with a vulnerability you don't often see in characters like that. It's endearing to people. I think with Mike being the leader of this new school of superheroes, he does an amazing job."
Theo Rossi, who plays the villain Shades, likens Colter's real-life persona to Cage.
"If you've ever been around Mike, talked or hung out with Mike, he is Luke Cage," Rossi said.
"I mean, he's massive. But at the same time, he's got a swagger and a personality that's so incredible."
- AP