Bowie's band reunited for a set covering hits such as Let's Dance and Under Pressure before Lorde joined for the grand finale of Life on Mars.
The singer passed away earlier this year after a battle with cancer.
David Bowie was one of Lorde's idols, the singer was able to meet the star before he passed away.
About the meeting with Bowie, she said in 2014: "To have someone like that tell you that listening to you felt like listening to tomorrow. I was like... I could creatively die and just be happy forever. I never tell anyone about that experience, because it meant so much to me, and I feel like it would be dulled or something if I always talked about it in magazines or whatever. It's my special thing."
"It was super cute, though-for some reason we were holding hands and just staring into each other's eyes and talking, and I was like, This is David Bowie's hand, what am I doing? It was insane. A beautiful moment."
Fans on Twitter were left "speechless" by her stunning performance: