"We would have been fine. I feel so strong with these people, and it's so appropriate. I belonged there."
Since Cannes, Stewart's personal life has unravelled as she admitted she cheated on Pattinson with her Snow White and the Huntsman director, Rupert Sanders.
The Toronto premiere of On the Road last week was Stewart's first public appearance since, and she was greeted by hundreds of Twilight fans who came out to show support for the 22-year-old actress.
"You expect a lot of people at a Twilight premiere, but showing up at an On the Road Toronto film festival screening and seeing that amount of people is absolutely, disarmingly amazing," Stewart said. "It felt pretty cool."
On the Road has been on Hollywood's to-do list for decades, but previous attempts to adapt it for film always fell through.
Salles (Central Station, The Motorcycle Diaries) spent years developing the film, which stars Hedlund as beat generation free spirit Dean Moriarty, inspired by Kerouac's friend Neal Cassady, and Sam Riley as the author's alter-ego, Sal Paradise.
Stewart co-stars as Dean's first wife, Marylou, who joins him and Sal on some of their crazed cross-country adventures.
"Marylou and Dean are the type of people that I was inspired by. Initially at 15, reading the book, going God, these are the sort of people I've got to find. The mad ones," Stewart said.
In November, Stewart faces some awkward public appearances when she and Pattinson will be promoting The Twilight Saga: Breaking Dawn - Part 2, the finale of their vampire romance.
Stewart is confident they will get through that all right.
"We're going to be fine," Stewart said. "We're totally fine."
Who: Kristen Stewart
What: On the Road
When: In cinemas on Thursday
-AAP