Jimmy Fallon is to replace Jay Leno on The Tonight Show.
The long-running host, who has helmed the show since taking over from Johnny Carson in 1992, will be departing from his job in 2014 when his contract expires, leaving Late Night presenter Fallon to take over.
According to The New York Times newspaper, the NBC programme will also move back to its original home of New York once the transition takes place, where it was founded with Steve Allen in 1954 before being moved to Burbank, California, in 1972 under the reign of Carson.
There was no mention of the switch during the programme, but Leno - who turns 63 next month - did criticise the network for their low ratings.
A senior executive taking part in the negotiations commented: "There is no way on earth that this is not going to happen."