Jamie Lee Curtis slams Donald Trump for sex talk regarding Lindsay Lohan

Jamie Lee Curtis and Lindsay Lohan in Freaky Friday.

Jamie Lee Curtis has slammed Donald Trump for sexual comments he made about an 18-year-old Lindsay Lohan's ability in bed.

Curtis, who starred with Lohan in the 2003 film Freaky Friday, came to her co-star's defence following a string of incidents in which Trump has been disrespectful to women.

Republican presidential candidate Donald Trump. Photo / AP

A recently rediscovered interview with Trump on the Howard Stern radio show features the Republican nominee for US president suggesting that the then 18-year-old Lohan would most likely be good in bed because she was so troubled.

"Can you imagine the sex with this troubled teen?" said Stern.

"Yeah, you're probably right," Trump said. "She's probably deeply troubled and therefore great in bed. How come the deeply troubled women, you know, deeply, deeply troubled, they're always the best in bed?"

Curtis wasted no time coming out swinging at Trump.

"I am appalled. Lindsay needed help and guidance. Not your gross, lecherous, lewd commentary. YOU are the Republican nominee for the Presidency. #wordsmattermrtrump @hillaryclinton #hillaryclinton" she wrote on Instagram.

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"Can you imagine the sex with this troubled teen?" said Stern. "Yeah, you're probably right," Trump said. "She's probably deeply troubled and therefore great in bed. How come the deeply troubled women, you know, deeply, deeply troubled, they're always the best in bed?" I am appalled. Lindsay needed help and guidance. Not your gross, lecherous, lewd commentary. YOU are the Republican nominee for the Presidency. #wordsmattermrtrump @hillaryclinton #hillaryclinton

A post shared by Jamie Lee Curtis (@curtisleejamie) on Oct 14, 2016 at 11:31am PDT

Lohan hasn't commented on Trump's words but her rep released a statement to CNN.

"Right now, Lindsay is choosing to focus on the positive things happening in her life and has decided to disregard the comments made about her by Presidential nominee Donald Trump. She is focusing on helping children around the world in need and that's where her passion is," the rep said.

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Freak Out Women Friday!During his speech, Trump questioned why Stoynoff waited more than a decade before going public with her story — she says she was triggered by hearing Trump categorically deny he’s ever sexually assaulted anyone during the second presidential debate — and then went after her looks. “Take a look. You take a look,” Trump said. “Look at her, look at her words, you tell me what you think. I don’t think so.” @hillaryclinton #hillaryclinton #imwithher #sheswithus #wereallinthistogether

A post shared by Jamie Lee Curtis (@curtisleejamie) on Oct 14, 2016 at 7:56am PDT

Lohan's movie career appeared destined to be spectacular after solid performances as a teenager. However, reports of heavy partying and turning up late on set saw her fall out of favour with Hollywood.