At his last show, at the Hollywood Bowl on September 15, Petty reportedly told the crowd: "I want to thank you for 40 years of a really great time."
Petty has released 13 albums with his band The Heartbreakers, along with three solo albums. His last was Hypnotic Eye in 2013.
Last week, the singer concluded his tour - which began in April earlier this year - at the Hollywood Bowl, and he previously admitted the run on the road would likely be his "last big one".
He told Rolling Stone: "We're all on the backside of our 60s... I have a granddaughter now I'd like to see as much as I can. I don't want to spend my life on the road. This tour will take me away for four months. With a little kid, that's a lot of time."
Along with his group, Tom Petty and the Heartbreakers became stars in 1976, going onto have a string of hits over a number of decades.
His biggest songs include Free Fallin', I Won't Back Down, Learning to Fly, American Girl, Refugee and I Won't Back Down.
He also spent time as a member of The Traveling Wilburys in the 1980s, and the supergroup boasted Bob Dylan, Roy Orbison, George Harrison and Jeff Lynne amongst its members