"I hope Beyonce ain't using the twins to feed the twins after that glass of wine... #ImJustSayin #IBelieveThatChildrenAreOurFuture," one user wrote.
It didn't take long for the Beyhive to come out in full force to defend their queen.
"It is insane for slamming a woman for having a glass of wine if she breast feeds. One unit of alcohol is out of your breast milk within two hrs. One glass of wine is not a crime lol! Chill out! You do you B," one fan wrote.
The comments extended beyond Instagram with many fans taking to other social media networks to express their opinion on the matter.
Beyonce shared the first picture of her twins, Sir and Rumi Carter, one month after they were born. She welcomed them with husband Jay Z in mid-June.