In a statement to the website, Fryer's family said she went to sleep and never woke up.
"True soulmates, Miranda and Arthur were making plans to start their family, when one day last week she went to sleep and never woke up. We do not know why," it said, referring to Fryer's husband Arthur Pothitis.
"She had had some health issues with her heart, maybe her beautiful persona was just too good for this world of ours. We, who all loved her so much, shall treasure the memories she has left us with and mourn our loss forever.
"A beautiful child, stunning teenager, beautiful inside, and out … a woman, with so much love and happiness given and received. So many friends, so much still to offer this world, gone."
Ms Fryer was the on screen daughter of Joe Mangel, played by Mark Little, and Kerry Bishop, played by Linda Hartley-Clark.
Her real-life mother Traci Hunter told the Herald Sun that she was only supposed to be on the show for six weeks but the storyline was extended and she was contracted for three years.
"She had so much fun on the show but when she was going to start school I really felt that it was not a good idea for her to continue as she deserved to have a childhood," Hunter said.
Fryer completed a certificate in hospitality and an art diploma before studying to be a nurse.
She recently finished her degree and was due to start a postgraduate position at Monash Hospital in the neuroscience department in February.
Hunter said she was the "most wonderful daughter".
"She had so much love and passion for life. She was a truly kind loving person, almost too good to be true – obviously she was too good to be true as she has been taken from us so early."