David Arquette can relate to Chaz Bono because his sibling Alexis also went through a sex change.
The Scream 4 actor is competing against Chaz - who was born a girl named Chastity and began gender reassignment surgery around three years ago - in the current series of Dancing with the Stars and says he knows what he is going through because his sister had a similar experience.
David told RadarOnline.com: "It's really admirable of him to step out and put up with the criticism and be himself, and be comfortable with himself. It's just been great.
"I didn't know Chaz before going on there, but with Alexis I saw how vicious people can be, and I saw what a real emotional journey it is for someone who doesn't feel comfortable in the sex that they were given as a child. So I understand how he feels, and I also see how natural it is."
David is sure Alexis - who is an actress and musician - will be watching the show but hopes she shows family loyalty when it comes to voting.