The move will further bolster the couple's coffers and complicate their divorce proceedings. Forbes estimates they earned $555 million since their relationship began and also lay claim to homes around the world, the philanthropic Jolie-Pitt foundation and Miraval Rose produced from their vineyard in France.
D-Resort officials declined to comment on Pitt's investment plans and his impending divorce from Jolie. However early reports from unnamed sources close to the couple claim Pitt will fight Jolie for custody of their six children.
Croatia-based architect Nikola Basic confirmed he accompanied Pitt to see possible investment areas for hotels and villas on the Adriatic Coast earlier this month.
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"He was mostly interested in the architecture and the tourist potential of the area," he said.
Local media have revealed Pitt's eventual investment would be made in conjunction with a Swiss financial fund and could be worth up to $3 billion (EUR2 billion).