It's Vogue's biggest and most influential edition, so important it has it's own documentary, The September Issue.
But in an unprecedented move, the style bible's editor-in-chief Anna Wintour has relinquished control over what is always the year's most talked about magazine cover - instead putting Beyonce in charge.
The surprise move is out of character for the infamously hands on editor, but is said to have been negotiated as a key part of Beyonce's contract, according to a Huffington Post report.
And the singer has used her power to give a career boost to 23-year-old black photographer Tyler Mitchell, recruiting him to take her picture.
He is the first photographer of color to shoot a Vogue cover. The magazine is 126 years old and first featured color photos on it's cover in 1932.