Clearly touched by the star, the young boy penned the letter in which he gushed over the star and her entry into the jungle.
He wrote: 'To Anne, My name is Joseph Hughes and I am 11. I live in Preston Lancashire and I go to a specialist school. I was diagnosed with autism when I was 5. I like to watch you on The Chase...
'And now, I have been watching you in the jungle. I couldn't go in there because there are too many bugs. You are very clever...
'Sometimes people are mean to me because I am autistic but watching you makes me see that other people have autism too and maybe I can have a cool job like you when I am older. So you like Thunderbirds? I love them...
'My favourite is Thunderbird 2. I have drawn you a picture, I hope you like it. Good luck in the jungle, I hope you like it. Love from Joseph.'
Today, Joseph's mother Kate Jarvis filmed her son's reaction as she told him his letter had gone viral.
She also told the youngster that the team behind Thunderbirds had been in touch, offering to send Joseph a gift.
The 11-year-old, who was filmed sitting on the sofa in his uniform before school, said he was 'really excited'.
While sharing the post, Toff revealed she 'loved it so much' while the image was attached to a message stating it 'gave the reader goosebumps'.
Speaking on Loose Women in September, Anne revealed she doesn't let anyone into her home or like to go on holiday as she prefers things to be quiet.
She explained that Asperger's makes her unorganised, which has given her a 'cluttered' house that she won't let anyone visit.
Anne said: 'People always say to me ''Where do you keep your autism?'' and I always says ''It's it's behind my front door and I'm not coming in.'''
She continued: 'I just need everything to go quiet, for people to stop bothering me and not thinking about when I'm going to get packed. I like to have my own kitchen so I can cook and a washing machine so I can do washing. The things you can't get in a hotel.'
Anne previously told how the condition had led to her misreading signals from potential love interests - but also believed it has helped her quiz knowledge.
She also revealed how the syndrome costed her a job in proof-reading as her inability to multi-task led to her under-performing.
The job loss left her on benefits and led to two bailiffs arrived within ten minutes of each other on New Year's Day 2008.
Anne later applied for The Chase with the help of a social worker. She has appeared on the show, which is presented by Bradley Walsh, since 2010.
