The Wall Street Journal reports such a significant settlement would represent a significant chunk of the company's reported US$200 million cash reserves as of the end of 2016. Theranos is still facing numerous lawsuits from disgruntled investors, customers, and its former retail partner Walgreens.
Theranos founder Elizabeth Holmes raised more than half a billion dollars from investors hyping the non-existent technology.
At its peak, the company was valued at $11.8 billion, putting Holmes' personal net worth at $5.9 billion, making her America's youngest female billionaire.
Among the company's high-profile investors were Rupert Murdoch, executive chairman of News Corp - publisher of news.com.au - and US Education Secretary Betsy DeVos. After the ruse was exposed, Theranos was embroiled in a string of investigations by numerous US authorities, leading to the closure of labs and the sacking of 340 staff.
The company is now attempting to develop a new product dubbed "miniLab", described as a "portable device ... the size of a microwave ... designed to have the capability to process and analyse very small samples of blood".
Theranos said in a statement that settling the PFM lawsuits "brings to a close the burden and expense of litigation and preserves resources to bring the miniLab platform to market".
In March, Theranos unveiled a plan to offer disgruntled investors extra shares in the company out of Holmes personal 50 per cent shareholding, in exchange for promises not to sue.