In many recent crypto hacking episodes, users did not receive their funds back since transactions typically cannot be reversed on blockchains.
Phantom, a wallet app built on Solana, and Solana non-fungible token marketplace Magic Eden were among the providers that said they were affected in the apparent hacking incident.
The Solana Foundation said wallets that allow traders to hold their coins offline rather than using online applications did not appear to have been affected.
Solana Labs, a developer of the Solana blockchain, is backed by big groups in traditional and cryptocurrency markets including venture capital company Andreessen Horowitz, high-speed trading shop Jump Trading, and Sam Bankman-Fried's Alameda Research.
Solana is designed to process up to 50,000 trades a second, a scale far in excess of rivals including bitcoin and ethereum, and on a par with established traditional financial services such as the Nasdaq stock exchange.
In January, Bank of America analysts said Solana "could become the Visa of the digital asset ecosystem".
However, Solana has suffered processing glitches that have tarnished its reputation.
The entirety of the Solana network went dark for four hours in June, an outage that was documented on the network's official status website.
The blockchain's eponymous native coin has tumbled almost 80 per cent this year, bigger than the drops sustained by its larger rivals bitcoin and ether.
-By Scott Chipolina in London