Concern about Greece after politicians delayed a second bailout to the debt-laden nation weighed on equities even as investors drew hope from Federal Reserve chief Ben Bernanke's promise that the US central bank is ready to act to save the world's largest economy.
In Europe, the Stoxx 600 Index closed the day with a 2.8 per cent drop.
Shares of Dexia SA plunged to a record as European finance ministers were considering making banks take bigger losses on Greek debt and postponed a crucial aid payment to Athens until mid-November.
Greek Finance Minister Evangelos Venizelos said the country had enough cash to cope until then and insisted that euro zone ministers were not preparing for a Greek default, despite the ominous delay.
"There is no discussion of default," Venizelos told a news conference on returning to Athens on Tuesday, according to Reuters.