Wall Street extended losses for a second day amid concern the Federal Reserve's stimulus for the US economy might end sooner than expected, while the latest data on euro zone services and manufacturing output showed a larger-than-expected contraction.
Minutes from the latest Fed meeting called into question the size and duration of the central bank's bond-buying program at a time when the signals about the recovery in the world's largest economy remain mixed, while the euro zone shows signs of further trouble.
A report today showed the Fed's Philadelphia general economic index slid to minus 12.5 in February, the lowest reading since June, from minus 5.8 in January.
In afternoon trading in New York, the Dow Jones Industrial Average dropped 0.54 per cent, the Standard & Poor's 500 Index declined 0.75 per cent, while the Nasdaq Composite Index weakened 1.15 per cent. The S&P 500 closed at a five-year high on Tuesday.
"People are taking some profits and watching to see what the next catalyst is," Neil Massa, senior equity trader at Boston-based John Hancock Asset Management, told Bloomberg News. "It's a healthy sell off. We've gone up so much, it's a good opportunity to take a breather. I don't think it's a sign of a continuing trend."