Stocks on both sides of the Atlantic slid amid renewed concern about the impact of Europe's debt crisis on the global economy after ECB chief Mario Draghi said the euro zone economy is expected to remain weak next year.
In addition, Greece may have to wait until next week to find out if its latest package of cost-cutting measures has satisfied EU demands.
In the US, the latest clues on the outlook for corporate earnings proved disappointing yet again including from MacDonald's which reported a decline in monthly store sales for the first time in nine years.
The latest US economic data were better than anticipated but failed to lift the mood. Initial claims for state unemployment benefits fell 8,000 to a seasonally adjusted 355,000 last week, the Labor Department said.
The monthly trade gap unexpectedly narrowed in September, shrinking to US$41.55 billion, according to the Commerce Department. That's the smallest deficit since December 2010.