The company plans to hire more than 100 support workers from around the region, who will all be able to avoid the dreaded commute by working from home or a place of their choice.
"The creation of 100 new jobs is a great story for the city," said Wellington Regional Economic Development Agency chief executive Lance Walker.
"One of the nice things about the model is actually opportunities for people who live in the Hutt or Porirua or Kapiti to also be part of this network as well."
It was good to see a global company such as Shopify recognising "the talent and the ecosystem that we have here".
"It's nice to have global brands choosing Wellington as a place to start up."
Walker thought the remote working model might spread over time.
"I think it's a reality that we're going to see a flexibility and importance of work-life balance drive change in the way that we manage workplaces," he said.
Murray said some workers functioned better in their own space.
Not relying on having an office space also allowed the company to move faster in setting up its base and hiring staff.
Mayor Justin Lester said he was "thrilled" the company was making Wellington its Oceania base.
It was a "true testament to the talent we have in the city".