Prof Roubini, an economist at New York University and founder of Roubini Global Economics, said Donald Trump's enormous fiscal blitz and his US$1 trillion ($1.5t) deficits at the top of the economic cycle had bought a short-term boom - at great long term cost - but it is a sugar-rush effect.
Asset markets will roll over next year and the US economy itself will hit the wall in 2020 with global consequences, he said.
"Fiscal stimulus will turn into fiscal drag. Subtracting 2 per cent of GDP by then," he said.
Italy's tensions have come off the boil over recent days as the Lega nationalist party and the Five Star movement tone down threats of a budget fight with the EU.
However, the coalition has sent mixed political messages, and has to meet at least some of its €75 billion ($132.7b) promises to electors. The test will come when hard figures are committed to paper next month.
Meanwhile, the US Federal Reserve will be tightening hard to head off incipient inflation, pushing up the Fed funds rate rapidly to 3.5 per cent.
This is a disaster in the making for emerging markets with large dollar debts and already under severe stress.
The ECB and the Bank of Japan are effectively holding down US long-term rates at the moment through globalised QE but this too is coming to an end.
"It is going to push US bond yields and tighten financial conditions," Prof Roubini said.
If that were not enough, China will be grappling with a deep secular -slowdown after years of "can-kicking" with excess credit creation and investment.
"By 2020 the Chinese will have to accept a 5 per cent growth potential," Prof Roubini said.
He described it as a "perfect storm" for the US, China and emerging markets, with a fragile Europe caught in the violent crosswinds.
Such an outcome would be intolerable for President Trump.
"So what is he going to do? He will attack the Fed. He will find a foreign policy crisis. He can't attack China because it is too big, so he will attack Iran and that will lead to a stagflationary shock," he said.
Prof Roubini's gloomy predictions have earned him the nickname "Doctor Doom". He gained fame as one of the few people to predict the financial crisis of 2008.