Wall Street moved lower amid further evidence of China's slowing economic growth, underpinning uncertainty ahead of this week's gathering of US Federal Reserve policy makers.
The Federal Open Market Committee will begin its two-day meeting on Wednesday, and might decide to hike interest rates for the first time since 2006.
In New York trading at about 3pm, the Dow Jones industrial average fell 0.47 percent, the Standard & Poor's 500 Index slid 0.47 percent, while the Nasdaq Composite Index retreated 0.37 percent.
"With the Fed coming out Thursday nobody wants to take any real shots," Michael Matousek, head trader at US Global Investors in San Antonio, told Reuters.
Declines in shares of Visa and those of Cisco, last down 1.4 percent and 1.3 percent respectively, led the Dow lower.
"They won't go, but they will convey a hawkish message to keep the markets on cue and prevent pricing from moving well into 2016," Gennadiy Goldberg, a New York-based US rates strategist with TD Securities, told Bloomberg. "The Fed will continue to string the market along and keep it primed for a rate hike. It will keep every meeting in play."
TD expects the Fed will raise rates in March.
Shares of Yahoo! and Alibaba slid, last down 3.3 percent and 3.1 percent respectively, after Barron's reported Alibaba's stock may drop another 50 percent amid China's economic struggles and increased competition. Alibaba begged to differ.