Stocks fell on both sides of the Atlantic as President Donald Trump formally ordered the US to withdraw from the Trans-Pacific Partnership trade deal, bolstering concern about the impact on corporate profits and economic growth.
Trump also prepared to sign executive orders to renegotiate the North American Free Trade Agreement, Bloomberg reported, citing an official familiar with the plans.
"After a period of investor optimism around Trump comes a time of investor concern connected to his protectionism policy," Andrea Tueni, a trader at Saxo Bank, told Bloomberg. "This puts investors in a wait-and-see mode, they might be expecting further declines."
Wall Street moved lower. In 1.10pm trading in New York, the Dow Jones Industrial Average declined 0.3 per cent, while the Nasdaq Composite Index fell 0.2 per cent. In 12.54pm trading, the Standard & Poor's 500 Index gave up 0.5 per cent.
"The markets are less enthusiastic about protectionism than they are about pro-growth policies such as cutting taxes and decreasing regulation," Art Hogan, chief market strategist at Wunderlich Equity Capital Markets, told Reuters.