The Dow weakened as declines in shares of DuPont and those of Caterpillar, down 1.7 per cent and 1.1 per cent respectively, outweighed gains in shares of UnitedHealth and those of Verizon Communications, up 0.7 per cent and 0.4 per cent respectively.
"It doesn't feel like the market is in panic, just that it is reassessing what the expectations were, and the expectations were we were going to get a lot of reforms quickly, and now it's clear that we're not," Ken Polcari, director of the NYSE floor division at O'Neil Securities in New York, told Reuters.
In Europe, the Stoxx 600 Index finished the session with a 0.5 per cent drop from the previous close. Germany's DAX Index shed 0.5 per cent, while the UK's FTSE 100 Index declined 0.6 per cent, and France's CAC40 Index dropped 0.7 per cent.
Reckitt Benckiser shares slipped 0.4 per cent in London. The company, which recently acquired Mead Johnson Nutrition, said it's considering a sale of its French's Food business.
Reckitt will begin a review and consider all options for the "non-core" business, according to media reports. French's Foods accounts for 4 per cent of Reckitt Benckiser's total revenue.
A possible price tag of 2 billion pounds, which the UK's Sunday Times newspaper reported, would imply a multiple of about 16 times earnings before interest, taxes, depreciation and amortisation, according to Bloomberg.
While that's above global food companies trading at 13.5 times on average, it's "probably justified by the strong fundamentals," Kepler Cheuvreux analyst Richard Withagen said in a note, Bloomberg reported.