Finally, aircraft would be able to be used more intensively, as they would not require rest days that pilots currently get.
UBS analysts Jarrod Castle and Celine Fornaro point out that similar "technology to remotely control military drones already exists and this could be adapted to civil applications".
They predict that the first aircraft to embrace self-flying technology will be those carrying only cargo, first removing one of the two pilots normally in the cockpit, then eventually replacing them altogether. Private jets are expected to follow, then helicopters, with airliners the last to adopt the new technology.
However, the research warns that while the savings generated by cutting out pilots might be attractive to to airlines - the concept isn't so warmly welcomed by passengers.
UBS's survey of 8,000 people found that 54 per cent of them wouldn't want to take a pilotless flight even if it were cheaper and only 17 per cent said they were likely to - a much lower level than those willing to travel in a driverless car.
British pilots' association Balpa also warned said it had "concerns" about "the excitement of this futuristic idea" - but noted that cockpits are already highly automated. Currently technology means that the majority flights are under the control of autopilot and modern aircraft can land without a human taking the controls.
But when things go wrong, Balpa said people want a human in the cockpit.
"Automation already supports operations but every single day pilots have to intervene when the automatics don't do what they're supposed to," said Steve Landells, Balpa flight safety specialist. "Computers can fail, and often do, and someone is still going to be needed to work that computer. Most of us own some sort of electronic device that can do amazing things - however, a human is still required to operate it."
Balpa doubts truly pilotless aircraft will ever be a reality, with it more likely that pilots will control airliners remotely from ground stations - but even this might not be enough to reassure passengers.
"Public perception is still uncertain when it comes to automation and many might still be uncomfortable knowing that their life is in the hands of someone sat in a control tower hundreds or thousands of miles away," said Landells. "Having a pilot on the aircraft who is as much at risk as the passengers is probably the surest guarantee of safety there can be."
If regulators can also be convinced and airlines can get passengers on board with the idea of pilotless planes, UBS believes there will be further opportunities across the aerospace sector.
Cockpits typically make up 5 per cent of the total cost of an aircraft and this could rise with the greater technology required for computer piloted aircraft, meaning suppliers could increase their prices. They could also offer higher margin "flight by the hour" deals where airlines pay for flight time, rather than buy an airliner outright and pay for it to be serviced.
It could also radically alter the current airline sector, with flight by the hour deals lowering costs to entry by reducing the capital outlay needed for new planes and and cutting out expensive crew training. This could mean new players entering the sector, having a huge impact on established "legacy" airliners and even low-cost carriers who have cut costs to the bone.