The Chiefs hemorrhaged points in the first half after having winger Chase Tiatia yellow carded for a deliberate knockdown 16 minutes into the contest, before first five-eighth Damian McKenzie was shown a red card for a high shot on Reds halfback Tate McDermott six minutes later.
The Chiefs conceded five tries between Tiatia's yellow card and halftime, and while they fought back once McKenzie could be replaced in the 43rd minute, their comeback bid fell just short.
While he was happy with how the side fought back, Chiefs coach Clayton McMillan noted the similarities between their game and the Warriors' NRL loss to the North Queensland Cowboys in Townsville the night before, a match the Chiefs were in attendance for.
The Warriors were also impacted by losing a man to the sin bin, and conceded two tries when they were down a player.
"[We] should have learned lessons there when the Warriors leaked two tries when they were down a man," McMillan said. "A little bit like them, we almost pulled off a Houdini act and came back, but we fell short and you have to give credit to the Reds who would have been disappointed with how things went last week against the Crusaders.
"We always expected a response and unfortunately for us we opened the door for them to do that. But good on them; good teams can cash in on those opportunities if you present them."
Being the first New Zealand team to drop a match in the competition, McMillan shared Weber's outlook for the season, but said that was no reason to approach the final two rounds any differently.
"I think the loss is terminal, we'll be gone. But we've got a young squad and while we're disappointed we won't be able to contest that final – I don't think, barring a minor miracle – we have to learn the lessons and come back better."