"It's believed he had a weapon and went into the shop and left with a yet to be determined amount of cash," Mrs Perk said.
No one was injured during the incident.
A 15 and 17-year-old were arrested for the robbery of the same store on Sunday in which they are accused of targeting synthetic cannabis.
The pair were later found by police at Riverholm Dr and Old Taupo Rd and all stolen property recovered. One of the offenders is due to appear in court today.
Police were still investigating the latest crime late yesterday and were unable to confirm if anyone had been arrested.
In November a man was arrested after walking into the store and producing what appeared to be a knife and demanding money.
Skingraft owner Dave Young said he saw police pull up across the road from his Pukuatua St shop and at the end of the streets yesterday.
"Police were stopping the buses and cars coming through and we thought it was just a fight," he said.
"We had just sent [Wild Things] flowers today as we felt for them for what happened on Sunday."
Mr Young, whose store also stocked synthetic cannabis, said selling the product didn't make them any more susceptible for theft or robbery.
"We have security cameras everywhere and there are always people in here," he said.
"Look at the statistics, dairies and liquor store outlets get robbed too and it's mainly because their store windows are covered, they're not visible from the street.
"If they banned legal highs in New Zealand for 30 days, see what happens," Mr Young said. "There will still be robberies."
Rotorua police are wanting to hear from anyone who may have been in Pukuatua St during the time of the robbery or anyone who may have seen anybody acting suspiciously in the area.