"We will protect the environment, but we are not going to see the economic future of Queensland shut down," the Premier said. "We are in the coal business. If you want decent hospitals, schools and police on the beat, we all need to understand that."
The federal Environment Minister, Tony Burke, agreed the reef was "at a crossroads", and said the Government was acutely aware of the challenges facing it, including climate change.
But he said he had no power to halt developments already approved.
The report expressed particular concern about the port expansion at Gladstone, one of the gateways to the southern reef, and about plans to build liquefied natural gas plants in Gladstone harbour. Dredging there has been blamed by environmentalists and fishermen for poor water quality and a skin disease affecting marine life.
Unesco noted "a continuing decline in the quality of some parts" of the reef.
Larissa Waters, a federal Greens senator, called on Burke to "press pause" on development in the area until a strategic assessment had been made.