A multi-vehicle crash has closed State Highway 1 near town of Marton in the Rangitīkei district and left two people injured.
Police said emergency vehicles were responding to a report of a two-vehicle crash shortly after 2pm.
Hato Hone St John said two ambulances, a rapid response unit, a helicopter, and a Prime unit had been sent in response.
One person in moderate condition was treated at the scene, and another person in serious condition was driven to Whanganui Base Hospital.