Nasties like poisons, solvents and batteries will be collected for safe disposal by Whanganui District Council next month.
"This is a really good opportunity to clear out your shelves and garages and make your home safer for children and pets," council waste adviser Stuart Hylton said.
This year's Household Hazardous Waste Day is on April 9 and everything to be collected must be registered online with the council by April 5.
People will then take their waste to a designated drop-off place at a set time. Registering in advance means arrangements can be made to dispose of the waste correctly.
Only household hazardous waste - and not commercial waste - will be accepted, Hylton said. Space is limited and the waste will be accepted on a "first in, first served" basis.