Whanganui fire crews were called to a large blaze at a central city house early on Friday morning.
Three fire engines arrived at the Wicksteed St property, in the block between London and Glasgow streets, around 2.20am and firefighters discovered the fire in the rear of the house.
A FENZ spokesman confirmed the house was unoccupied and was well alight when fire crews arrived.
Fire and Emergency Whanganui station officer Jason Hamlin said there is significant damage to the right rear end of the property.