Of particular concern was malignant, or critical pertussis, which created complications that could be fatal. Those most at risk of malignant pertussis were unimmunised newborns and infants (four to six weeks) who had had only one vaccination. Those infants were most likely to develop pneumonia, have a very high white blood cell count and high blood pressure in their lungs.
"Caring for very sick babies with severe pertussis can be extremely difficult on our staff, and parents often express feelings of guilt, knowing that their baby has a preventable illness," Dr Ganeshalingham said. Six of 11 young victims of malignant pertussis over the last 10 years had died.
Fellow paediatric intensivist Dr Fiona Miles agreed that the death of an infant from whooping cough had a huge impact on their families and doctors.
"It's really distressing for the whole team to be unable to save these babies, and to see the raw grief of parents losing a baby," she said, but ensuring that vaccinations were carried out on time and that all family members who came into contact with infants were immunised would help stem outbreaks.
"The main group we need to worry about are the very small babies, newborns who are too young to be immunised and have no protection. What that means is we need to be very vigilant about immunising everyone around them.
"The vaccine doesn't last forever, so people who haven't been immunised since they were children have low immunity, and if there's an outbreak then it's very easy for it to be transmitted on," she added.
Vaccination at six weeks, three months and five months was one of the most effective ways of protecting infants. Vaccination is free for children and pregnant women at between 28 and 38 weeks.